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Differences in prevalence and associated factors between mild and severe vertebral fractures in Japanese men and women: The third survey of the ROAD study

Journal of Bone and Mineral Metabolism Jan 08, 2019

Horii C, et al. - Using whole-spine radiographs, researchers studied 506 males (mean age 66.3 years) and 1,038 females (mean age 65.3 years) to assess the associated factors and variations in prevalence between mild and severe vertebral fracture (VF) in Japanese men and women. They used Genant’s semiquantitative method (SQ) to define VF (SQ ≥ 1 as VF, SQ = 1 as mild VF and SQ≥ 2 as severe VF). They noted that males had a higher prevalence of mild VF (21.2%) while females had significantly more prevalent severe VF. They found low back pain and reduced walking ability independently linked to severe VF, though not mild VF. They recorded the distribution of VF with two peaks concerning site—one large peak at the thoracolumbar region, and the other at the middle thoracic lesion.

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