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Dietary intake and serum levels of trans fatty acids and risk of breast cancer: A systematic review and dose-response meta-analysis of prospective studies

Clinical Nutrition Apr 02, 2019

Anjom-Shoae J, et al. - In a dose-response meta-analysis, investigators researched the relationship between dietary consumption and serum levels of trans fatty acids and breast cancer risk. They noted no significant relationship between dietary intake of conjugated linoleic acid (CLA) and breast cancer risk after combining three effect sizes from two prospective and one nested case-control study. They did not find any significant association of each additional 1 g/day dietary intake of total trans fats with a risk of breast cancer on the basis of five effect sizes. Ultimately, breast cancer risk did not seem linked with dietary intake of trans fatty acids, but, among postmenopausal females only, they did report a relationship between breast cancer risk and serum levels of trans fats.

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