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Dietary B vitamin intake is associated with lower urinary monomethyl arsenic and oxidative stress marker 15-F2t-isoprostane among new Hampshire adults

The Journal of Nutrition Nov 09, 2017

Howe CG, et al. - The authors aimed to investigate whether higher B vitamin intake was correlated with enhanced arsenic metabolism and lower concentrations of preclinical markers of cardiovascular disease (CVD) among New Hampshire adults. Higher intakes of certain B vitamins (particularly thiamin and vitamins B-6 and B-12 from food sources) might reduce the proportion of monomethyl arsenic species in urine (uMMA), an intermediate of arsenic metabolism that has been associated with an increased risk of CVD, among New Hampshire adults. Furthermore, higher overall B vitamin intake could reduce urinary 15-F2t-isoprostane (15-F2t-IsoP), a marker of oxidative stress and the potential risk factor for CVD, in part by reducing the proportion of uMMA.
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