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Dietary and supplemental antioxidant intake and risk of major adverse cardiovascular events in older men: The Concord Health and Ageing in Men Project

Nutrition, Metabolism & Cardiovascular Diseases Dec 11, 2020

Das A, Cumming RG, Naganathan V, et al. - Researchers investigated older Australian men to determine the risk of major adverse cardiovascular events (MACE) in relation to antioxidant intake in this population. They analyzed 794 men aged ≥ 75 years who took part in the 3rd wave of the Concord Health and Ageing in Men Project. They compared participants’ consumption of vitamins A, E, C and zinc to the Nutrient Reference Values for Australia, to evaluate dietary adequacy of antioxidant intake. They also evaluated usage of antioxidant supplements. A composite MACE endpoint, defined as having one of the following: death, myocardial infarction, ischemic stroke, congestive cardiac failure (CCF), and revascularization during observation span, was assessed. Findings revealed that among older Australian men, inadequate dietary antioxidant consumption, especially zinc, was related to elevated risk of CCF but not related to overall MACE.

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