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Diagnostic utility of bronchoalveolar lavage in children with complicated intrathoracic tuberculosis

Pediatric Pulmonology Apr 09, 2021

Goussard P, Croucamp R, Bosch C, et al. - Among children with complicated pulmonary tuberculosis (PTB), the usefulness of Xpert MTB/RIF assay (Xpert) on bronchoalveolar lavage (BAL) samples was inquired. Children with clinically diagnosed PTB, who had routine bronchoscopy over a five year span at a large referral hospital, were examined retrospectively. Antituberculosis treatment was received for a median of 10 days, at the time of bronchoscopy, by 112/146 (76.7%) children (median age 16 months). Findings revealed a high diagnostic yield conferred by Xpert testing of BAL in children already on antituberculosis treatment, in a pediatric population receiving bronchoscopy for complicated PTB. Consideration should be given to bronchoscopy if non‐invasive respiratory specimens fail to corroborate complicated TB.

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