Melachuri SR, Melachuri MK, Anetakis K, et al. - A retrospective observational study was performed to ascertain the clinical implications of low stimulation thresholds. Between 2010 and 2012, researchers included patients with pedicle screw stimulation testing who had undergone posterior lumbar spinal fusions at the University of Pittsburgh Medical Center were included in the study. The sensitivity, specificity, and diagnostic odds ratio were assessed to identify how effectively low pedicle screw responses predict new postoperative lower extremity neurological deficits. It was shown that individuals with pedicle screw stimulation thresholds less than or equal to 8 mA are 4.34 times more likely to have neurological clinical manifestations. They further observed that smoking and lower extremity deficits were shown to be significantly associated with pedicle screw stimulation thresholds less than or equal to 8 mA. They recorded that the low stimulation thresholds result in high specificity of 90%. The study demonstrated that the pedicle screw stimulation less than or equal to 8 mA can serve as an accurate rule-in test for the postoperative neurological deficit, warranting reevaluation of screw placement and/or replacement intraoperatively.