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Diagnostic accuracy of postmortem ultrasound vs 1.5T postmortem MRI for non‐invasive perinatal autopsies

Ultrasound in Obstetrics & Gynecology Mar 16, 2020

Shelmerdine SC, et al. - This study intended to ascertain the accuracy rate of both modalities in the same patient cohort, and determine whether post‐mortem ultrasound (PMUS) could provide the same information as post‐mortem MRI (PMMR). Researchers carried out 1.5 PMMR and PMUS in an unselected cohort of perinatal deaths in this prospective, 5 year (2014 – 2019) single centre study. They estimated the diagnostic accuracy rates for both modalities, applying autopsy as reference standard. As a secondary objective, this study measured the concordance rates for five anatomical regions (brain, spine, thorax, heart and abdomen) and overall main diagnosis for both modalities. A total of 136 cases were included who underwent both PMUS and PMMR. A high concordance rate for overall diagnosis implies that PMUS could be applied for triaging cases where PMMR access is limited or unavailable, although there are fewer non‐diagnostic cases using PMMR.   .

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