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Diagnostic accuracy of optical coherence tomography angiography in the detection of neovasculature in age-related macular degeneration: A meta-analysis

Acta Ophthalmologica Jul 30, 2021

Maesa JM, Baños-Álvarez E, Rosario-Lozano MP, et al. - In this systematic review and meta-analysis, researchers sought to assess the diagnostic accuracy of optical coherence tomography angiography (OCTA) in the identification of choroidal neovascularization due to age-related macular degeneration (AMD) in comparison with fluorescein angiography (FA). Studies that compared OCTA with FA for the diagnosis of choroidal neovascularization due to AMD and included data on the test's diagnostic validity or the data required for its calculation were chosen. The total population involved in the calculation comprised 553 eyes. The evidence obtained does not support OCTA's superiority over FA. Its application as a support technique has the potential to improve patient flow and reduce the number of FA.

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