Na A, Oppermann LM, Jupiter DC, et al. - Through searching MEDLINE/PubMed, CINAHL, PsycINFO, and Web of Science to August 201, researchers conducted this prognosis systematic review to compare physical function, pain, impairments (stiffness, range of motion, and strength), and health-related quality of life (HRQOL) outcomes between patients with and without diabetes mellitus, before and after total knee arthroplasty (TKA). Longitudinal studies that looked at physical activity, pain, impairments, and HRQOL outcomes in TKA patients with and without diabetes were included. Participants in the study were 17,472 patients. Before and after TKA, patients with diabetes mellitus had poorer patient-reported and clinician-assessed results. Given the limitations of the studies used, future research could alter these findings.