Kamil S, Sehested TSG, Carlson N, et al. - Researchers used nationwide registers to select and examine patients with varying degrees of coronary artery disease (CAD) characterized by coronary angiography (CAG) in order to determine how the risk of peripheral artery disease (PAD) in these individuals is influenced by diabetes mellitus (DM). They identified 116,491 patients (aged ≥ 18 years) undergoing first-time CAG between 2000 and 2012, among whom 20.58% had DM. For no-vessel disease, single-vessel disease, double-vessel disease, triple-vessel disease, and for diffuse disease, the cumulative-incidence of PAD in DM patients vs non-DM were 8.8% vs 4.9%, 8.2% vs 4.8%, 10.2% vs 6.0%, 13.0% vs 8.4%, and 6.8% vs 6.1%, respectively. Overall, in patients with and without established CAD, DM appears to be linked to increased risk of PAD, with increasing risk in more extensive CAD.