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Dexamethasone use in the treatment of pediatric deep neck space infections

Annals of Otology, Rhinology & Laryngology Dec 07, 2019

Tansey JB, Hamblin J, Mamidala M, et al. - In the treatment of pediatric deep neck space infections (DNSI) in combination with IV antibiotics, researchers evaluated the outcome of Intravenous (IV) dexamethasone. From March 2014 to June 2016, pediatric patients admitted for a DNSI were included. The comparison was made between patients treated with antibiotics alone and antibiotics and dexamethasone. A total of 153 DNSI patients, including 62 lateral neck, 18 parapharyngeal, 40 peritonsillar, 32 retropharyngeal, and 1 submandibular, were identified. Antibiotics are given to all patients. In 35% of patients, dexamethasone was used. According to this retrospective chart review, the dexamethasone and non-dexamethasone group had a surgical drainage rate of 36% and 53% respectively. MRSA, MSSA, and Streptococcus pyogenes were the most common microorganisms cultured. In pediatric patients with DNSI, dexamethasone use was related to a reduced rate of surgical drainage.
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