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Development of osteoarthritis in patients with degenerative meniscal tears treated with exercise therapy or surgery: A randomized controlled trial

Osteoarthritis and Cartilage Apr 02, 2020

Berg B, Roos EM, Englund M, et al. - This study was attempted to assess progression of individual radiographic features 5 years following exercise therapy or arthroscopic partial meniscectomy as treatment for degenerative meniscal tear. Researchers designed a randomized controlled trial to enroll a total of 140 adults, aged 35–60 years, with a magnetic resonance image verified degenerative meniscal tear, and 96% without definite radiographic knee osteoarthritis. Individuals were assigned randomly to either 12-weeks of supervised exercise therapy or arthroscopic partial meniscectomy. The primary endpoint included between-group difference in progression of tibiofemoral joint space narrowing and marginal osteophytes at 5 years, assessed semi-quantitatively by the OARSI atlas. The incidence of radiographic knee osteoarthritis and symptomatic knee osteoarthritis, medial tibiofemoral fixed joint space width (quantitatively assessed), and patient-reported outcome measures were considered as secondary endpoints. After surgical and non-surgical treatment, the research was inconclusive with respect to potential differences in progression of individual radiographic features for degenerative meniscal tear. Moreover, no strong evidence was obtained in support of differences in development of incident radiographic knee osteoarthritis or patient-reported outcomes between exercise therapy and arthroscopic partial meniscectomy.

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