Michalek-Zrabkowska M, Wieckiewicz M, Smardz J, et al. - Due to the possible impact on cardiovascular (CV) risk among relatively young and healthy patients, researchers aimed at determining the inflammatory markers, hormonal disturbances, and sleepiness associated with sleep bruxism (SB). Single-night polysomnography was conducted on a total of 74 individuals with probable SB, as well as a blood panel and 24-hour urinary excretion tests. Among participants, 78.4% had SB. They noted a positive correlation of the bruxism episode index (BEI) with urine concentrations of 17-hydroxycorticosteroids, C-reactive protein, and fibrinogen. Sleep bruxers vs nonbruxers showed significantly increased sleepiness. Per findings, participants with SB exhibit metabolic and hormonal disturbances, which likely result from stress and sympathetic activity. Moreover, due to the raised level of inflammatory and stress markers, young sleep bruxers may have a high CV risk.