Maher JM, et al. - In the present study, the researchers evaluateD the impact of baseline (ie, at diagnosis) and surveillance (ie, subsequent time points following diagnosis) imaging on management of high-risk cutaneous squamous cell carcinomas (HRCSSCs). To identify tumors that underwent baseline or surveillance imaging, all primary CSSCs treated at Brigham and Women’s Hospital (BWH) Mohs Surgery Clinic and Dana-Farber Cancer Institute High-Risk Skin Cancer Clinic from January 1, 2017, to June 1, 2019, were reviewed. Eighty-three individuals had imaging for 87 primary HRCSCCs, of which 48 had surveillance imaging. One hundred forty-six abnormal results were obtained from 248 imaging studies. Most detections were not initially seen, but rather during the 2-year posttreatment surveillance imaging. Imaging identifies HRSCC's subclinical disease. Prospective studies are required to identify best practices in HRCSCC for screening and surveillance.