Lu ES, Cui Y, Le R, et al. - In this prospective, observational study, researchers sought to compare the effectiveness of diabetic retinal neovascularisation (NV) detection utilizing the widefield swept-source optical coherence tomography angiography (WF SS-OCTA) vitreoretinal interface (VRI) Angio slab and SS-OCT VRI Structure slab. This investigation was conducted at Massachusetts Eye and Ear from January 2019 to June 2020. Proliferative diabetic retinopathy (PDR) patients, non-proliferative diabetic retinopathy patients, and diabetic but non-diabetic retinopathy patients were included in the analysis. Eighty-nine participants (142 eyes) were included in the study. According to findings, WF SS-OCTA 12×12 mm VRI Angio and SS-OCT VRI Structure imaging centred on the fovea and optic disc identified NV with high sensitivity and low false positives. The VRI slab may be useful in clinical practice for diagnosing and monitoring PDR.