Errichetti E, Geller S, Zalaudek I, et al. - Dermatoscopic clues are exhibited by nodular/plaque-type primary cutaneous lymphomas (PCLs). These clues could partially differ by histologic subtype and their diagnostic significance relies on the considered clinical differential diagnoses.

• There exists limited data regarding dermatoscopy of nodular/plaque-type T-/B-cell PCLs.

• This is a retrospective, multicenter case-control analysis of 261 lesions (121 PCLs and 140 controls).

• In multivariate analysis, orange structureless areas most strongly predicted PCL dermatoscopically, vs tumors and noninfiltrative inflammatory dermatoses.

• A positive link was identified between PCLs and either unfocused linear vessels with branches or focal white structureless areas vs infiltrative inflammatory dermatoses, whereas white lines predicted PCLs over pseudolymphomas.

• Vascular pattern differed between B- and T-cell PCLs and among B-cell PCL subtypes.