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Delayed cerebral ischaemia in patients with aneurysmal subarachnoid haemorrhage: Functional outcome and long-term mortality

Acta Anaesthesiologica Scandinavica Jun 16, 2019

Olsen MH, et al. - Researchers focused on the link between delayed cerebral ischaemia (DCI), functional outcome and 4-year mortality among patients with aneurysmal subarachnoid haemorrhage (aSAH) in this retrospective cohort study. DCI was defined as either a reduction in consciousness or focal neurological deficits lasting ≥1 hour without any other detectable cause. Three groups of patients were defined: those with DCI; those without DCI; or those who were unassessable for DCI. Overall 492 cases of aSAH were documented. The best functional outcome (modified Rankin Scale) was seen in patients without DCI vs patients with DCI and patients who were unassessable; furthermore worse outcomes were seen in the latter when compared with patients with DCI. Compared to patients without DCI, a significantly higher mortality was seen in those diagnosed with DCI, even ignoring the first 14 days post-admission. Overall, a possible association of DCI with both short- and long-term morbidity and mortality was suggested in patients with aSAH.
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