Toh RX, Yeo ZN, Liow MHL, et al. - This study sought to present the outcomes of debridement, antibiotics and implant retention (DAIR) and investigate the predictive prognostic factors. Researchers retrospectively examined 106 DAIRs. They characterized failure as requiring removal of total knee arthroplasty (TKA) implants. They examined predictive factors that may influence success of DAIR treatment such as age, gender, body mass index, ethnicity, American Society of Anesthesiologists score, comorbidities, preoperative erythrocyte sedimentation rate (ESR) and C-reactive protein, symptom duration, time between total knee arthroplasty and DAIR, cultures, rifampicin use, polyethylene liner change, and antibiotic duration. It was shown that DAIR failure is correlated with earlier time to mortality. According to the findings, repeat DAIRs, elevated ESR > 107.5, and S aureus periprosthetic joint infection are correlated with treatment failure and 2-stage revision is recommended.