Tritt A, et al. - Between 2013 and 2015, researchers examined 66 patients at the Montreal Children's Hospital to assess the effectiveness and safety of daily administration of intravenous antibiotics (mean duration of therapy 4.1 days) and physician evaluation in periorbital cellulitis secondary to acute sinusitis or upper respiratory tract infection. All children received ceftriaxone, with one patient also receiving cefuroxime. Complications were seen in one subject admitted for failure to improve/subperiosteal phlegmon who later underwent functional endoscopic sinus surgery, and one with eyelid abscess. They noted no severe neurological or visual deficiencies among the candidates. Ultimately, they recommended such intravenous therapy with daily reassessment by a practitioner as a safe choice in periorbital cellulitis without systemic signs of sickness.