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Creating a 13-year national longitudinal cohort of Veterans with chronic kidney disease

BMC Nephrology Jul 09, 2019

Ozieh MN, et al. - Given that several factors, including the high proportion of missing race data etc, have limited the development of large-scale chronic kidney disease (CKD) cohorts within the Veterans Affairs system, researchers created a large cohort using robust Kidney Disease: Improving Global Outcomes suggestions for detecting and staging CKD in order to address the limitations of previous investigations. A national cohort of Veterans with CKD was created by linking various patient and administrative files from the Veterans Health Administration National Patient Care. A CKD diagnosis throughout the study duration was supported by nearly 50 million observations gathered that corresponded to 3,051,001 unique veterans; non-Hispanic white constituted 80.9%, non-Hispanic black 13.4%, Hispanic 3.6%, and 2.0% were in other groups. The mean age was estimated to be 76.7, nearly 97% were male, and death before January 2016 was reported in 50.2%. Progression to stage 4 was reported in 12.3% of those with stage 3, and progression to stage 5 was seen in 21.6% of those with stage 4. Of overall patients, 98% were detected by estimated glomerular filtration rate values calculated from serum creatinine levels, while ICD-9 codes resulted in the identification of about 11.4% of patients; only 6.4% could be recognized via both sources. The answers to numerous questions in future investigations would be framed with the help of the findings in this 13-year national cohort.
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