Cranial ultrasound and neurophysiological testing to predict neurological outcome in infants born very preterm
Developmental Medicine & Child Neurology Jul 12, 2018
Franckx H, et al. - The accuracy of neuroimaging and neurophysiological tests in infants born very preterm were assessed in this retrospective cohort study. Participants in the study were 163 children born before 32 weeks gestational age. For this analysis, the researchers compared the accuracy of early and late cranial ultrasound (CUS), magnetic resonance imaging, somatosensory evoked potentials after stimulation of the posterior tibial nerve, and electroencephalography in predicting adverse neurodevelopmental outcome at the age of 2 years 6 months by calculating positive and negative likelihood ratios. In infants born preterm, none of the diagnostic tests had satisfactory performance in predicting future neurodevelopmental problems. The data showed only minimal influence on the probability of an adverse neurological outcome resulting from a normal test result.
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