COVID-19 severity and outcomes in patients with cancer: A matched cohort study
Journal of Clinical Oncology Oct 02, 2020
Brar G, Pinheiro LC, Shusterman M, et al. - Researchers analyzed 585 patients who tested COVID-19 (SARS-CoV-2) positive, 117 of whom had active cancer, to ascertain if worse outcomes were experienced by patients with cancer vs those without cancer. They also investigated demographic as well as clinical predictors of morbidity and death in patients with cancer. In terms of age, sex, and number of comorbidities, Patients with cancer were matched 1:4 to controls without cancer. According to the findings, presenting symptoms, in-hospital complications, and outcomes were observed to be comparable between patients with COVID-19 and cancer vs matched patients without cancer. This observation indicates that worse COVID-19 outcomes were not predicted by a diagnosis of active cancer alone and recent anticancer therapy, and thus, it is mandatory to carefully consider recommendations to limit cancer-directed therapy in relation to cancer-specific outcomes and mortality.
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