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COVID-19-associated mortality among kidney transplant recipients and candidates in the United States

Clinical Journal of the American Society of Nephrology Nov 12, 2021

Mohan S, King KL, Husain SA, et al. - Using national registry data for waitlisted candidates and kidney transplant recipients, researchers sought to report on mortality patterns among kidney transplant candidates and recipients during the COVID-19 pandemic in the United States.

  • Candidate and recipient populations were examined for excess all-cause deaths in 2020 and deaths directly attributed to COVID-19 in relation to prepandemic mortality patterns in 2019 and 2018.

  • Relative to the previous year, 24% higher all-cause mortality was recorded on the transplant waitlist; deaths were more frequently reported among those who were male, obese, and belong to a racial/ethnic minority group.

  • Although COVID-19 attributed to 11% of deaths on the waitlist in 2020, the remainder of the difference in mortality is also linked with COVID-19 to the extent that the pandemic has adversely influenced access to and delivery of healthcare, particularly during the peak of the initial surge.

  • Recipients who died of COVID-19 were more frequently younger, more likely to be obese, had lower educational attainment, and were more likely to belong to racial/ethnic minority groups when compared with those who died of other causes in 2020 or 2019.

  • Overall, in 2020, waitlisted candidates and kidney transplant recipients had higher rates of mortality linked with COVID-19.

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