Sayah DN, Szigiato AA, Mazzaferri J, et al. - Researchers conducted this prospective cross-sectional study to assess the non-invasive measurement of ocular rigidity (OR), an important biomechanical property of the eye, as a predictor of intraocular pressure (IOP) elevation after anti-vascular endothelial growth factor (anti-VEGF) intravitreal injection (IVI). Participants in the study were patients requiring IVI of anti-VEGF for a preexisting retinal condition. OR was evaluated in 18 eyes of 18 candidates using video-rate optical coherence tomography to measure pulsatile choroidal volume change, and pulsatile IOP change using dynamic contour tonometry. Data reported that the average increase in IOP following IVI was 19 ± 9 mm Hg, with a range of 7–33 mm Hg. The data presented in this work showed a strong positive association between OR and acute IOP elevation following IVI. Such results suggest that non-invasive OR measurement may be an important method for recognizing patients at risk of IOP spikes after IVI.