Komaru Y, Inokuchi R, Iwagami M, et al. - By performing a systematic review of relevant studies, researchers inquired about the correlation between acute kidney injury (AKI) incidence and its associated mortality. The included studies were identified from ­MEDLINE, EMBASE, and Cochrane Library, from 2004 to 2018. Studies involving a small number of participants (< 500 for adult cohorts, 50 for pediatric cohorts) were rejected. They used a regression model to assess the correlation among AKI incidence, death, and AKI-attributable fraction of death. Overall 287 eligible cohorts were analyzed. Within adult cohorts, they noted raised mortality of AKI patients but a reduction in the attributable fraction of mortality with the increasing AKI incidence. A lower crude AKI patients’ mortality was seen in both more recent publications and higher gross domestic product countries, though no reduction was evident in AKI-attributable fraction. Findings revealed a relatively low AKI-attributable mortality fraction in cohorts with high AKI incidence, this indicates a benefit of more experienced AKI management.