Cahn BA, Bartholomew TS, Patel HP, et al. - In the era of fentanyl and now stimulant coinjection, change may have occurred in risk factors linked with wounds and skin infections amongst persons who inject drugs. Six hundred seventy-five persons who inject drugs in a syringe services program were assessed for the number of injection site wounds and skin infections and for the correlated factors. In this sample, 307 wounds and skin infections were reported in 173 participants. Age 30 or older, female gender, ever experiencing homelessness, cocaine injection, and injecting between 5 and 10 years were identified as significant factors linked with elevated number of wounds and skin infections. These findings suggest a common occurrence of wounds and skin infections amongst syringe services program clients and their association with certain risk factors that may aid in designing effective interventions.