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Correlates of future violence in people being treated for schizophrenia

American Journal of Psychiatry May 04, 2019

Buchanan A, et al. - Researchers performed the first longitudinal multivariable analysis assessing predictors of violence in a large cohort of schizophrenic individuals. They examined 1,435 individuals with schizophrenia who participated in the National Institute of Mental Health’s Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) study. During the 18 months of follow-up, there were reports of participating in injurious violence for 77 participants (5.4%) and participating in exclusively noninjurious violence for 119 (8.3%). Future injurious violence was noted to be correlated with baseline injurious violence, recent violent victimization, severity of drug use, baseline noninjurious violence, childhood sexual abuse, and medication nonadherence. They identified baseline noninjurious violence to be the strongest predictor for participants with no history of injurious violence at study entry. They recommend emphasizing medication adherence in treatment strategies to reduce risk.

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