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Correlates of future violence in people being treated for schizophrenia

American Journal of Psychiatry Sep 17, 2019

Buchanan A, et al. - The correlates of violence among individuals with schizophrenia were investigated, which may assist in better risk assessment and care. This study was identified as the first longitudinal multivariable analysis addressing this topic in a large cohort of patients with schizophrenia followed over 18 months. Researchers examined a total of 1,435 individuals with schizophrenia who participated in the National Institute of Mental Health’s Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) study. Of these, 77 (5.4%) were recorded to have engaged in injurious violence during the follow-up period, and 119 (8.3%) were recorded to have engaged in exclusively noninjurious violence. In the multivariable analysis, future injurious violence was identified to be correlated with baseline injurious violence, recent violent victimization, severity of drug use, baseline noninjurious violence, childhood sexual abuse, and medication nonadherence. The strongest predictor was baseline noninjurious violence for participants with no history of injurious violence at study entry.
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