Dzaye O, Berning P, Dardari ZA, et al. - By investigating 6,271 Multi-Ethnic Study of Atherosclerosis (MESA) participants, aged 45–84 and without known cardiovascular disease (CVD) or self-reported history of cancer, researchers herein explored how coronary artery calcium (CAC) was related to incident cancer subtypes in the MESA. Mean follow-up of 12.9 ± 3.1 years revealed 777 incident cancer cases. The study sample had a mean age of 61.7 ± 10.2 years, 52.7% were females, and 36.5% were White. Findings revealed that in both genders, there was an association of CAC scores with cancer risk; however, this was identified to be stronger for lung and colorectal relative to sex-specific malignancies. Potential synergistic use of CAC scores in the detection of both CVD and lung and colorectal cancer risk, is supported by these findings.