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Coronary artery calcium in patients with schizophrenia

BMC Psychiatry Aug 28, 2021

Trab T, Attar R, Jensen SE, et al. - The data demonstrated that in patients with schizophrenia, the amount of coronary artery calcium (CAC) follows norm percentiles, and variables correlated with the CAC score are similar in patients with schizophrenia and the general population. The results illustrated that in patients with schizophrenia, the CAC score may not be sufficient to detect the risk of coronary heart disease (CHD). There is a need for future studies to explore other measures of subclinical CHD, including measures of peripheral atherosclerosis or cardiac autonomic neuropathy to improve early detection and intervention.

  • Researchers recruited a total of 127 (77.9%) patients who had a CAC score below or equal to the matched 50th, 20 (12.3%) above the 75th, and nine (5.5%) above the 90th percentile.

  • It was shown that male gender (P < 0.05), age (P < 0.001) and smoking (P < 0.05) were correlated with the presence of CAC while age (P < 0.001) and diabetes (P < 0.01) were correlated with the extent of CAC.

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