ter Telgte A, Wiegertjes K, Gesierich B, et al. - Among 54 elderly people with small vessel disease (SVD), researchers performed monthly 3T MRI for 10 consecutive months in order to investigate the contribution of acute infarcts, evidenced by diffusion-weighted imaging positive (DWI+) lesions, to progression of white matter hyperintensities (WMH) and other cerebral SVD markers. In 9 of 54 people included, 39 DWI+ lesions were detected on 21 of 472 DWI scans. They found that only a small proportion of the total WMH progression was explained by DWI+ lesions. Therefore, factors other than acute infarcts appeared to be the driver of WMH progression, most of the time. They also noted that the majority of incident lacunes and small cavities, and almost one-third of incident microbleeds, were explained by DWI+ lesions; this corroborates that despite being heterogeneous on MRI, WMH, lacunes, and microbleeds can have a common initial appearance on MRI.