Poinen K, et al. - In this observational retrospective cohort study, researchers intended to better characterize the risks associated with central venous catheter (CVC) use and their relationship to patient age in 1,041 patients older than 18 years from 5 Canadian dialysis programs who initiated outpatient maintenance hemodialysis therapy with a tunneled CVC between 2004 and 2012 and who had no creation of an arteriovenous fistula or arteriovenous graft. Complications were reported in nearly one-third of hemodialysis patients who used tunneled CVCs during 1 to 2 years. At 1 year, the occurrence of bacteremia was detected in ∼9% of patients. Also, most of the CVC-related hospitalizations were attributed to bacteremia. CVC-related death was infrequent. Lower rates of CVC complications were seen in patients aged 70 to 79 and those 80 years or older vs patients younger than 60 years.