Huang CJ, et al. - Using Taiwan’s National Health Insurance Research Database, researchers here examined the correlation between major depressive disorder (MDD) and the competing risk of Alzheimer dementia (AD) and non-Alzheimer dementia (NAD). The database yielded data of 13,067 patients with MDD and 52,268 non-MDD controls matched by index date, age, gender, geographical area, monthly income, and selected comorbidities through propensity score matching. AD developed in 335 (2.6%) of the 13,067 MDD patients and 313 (0.6%) of the 52,268 non-MDDs. NAD developed in 73 (0.59%) of the 13,067 MDD patients and 80 (0.15%) of the 52,268 non-MDD. Observations thereby suggest significantly higher incidence rates of AD and NAD among patients with MDD than the controls; this was particularly noted among aged 65 and above.