Oh SK, et al. - A retrospective study was designed to explore the impact of total intravenous anesthesia (TIVA) vs inhalation anesthesia (INHA) on the postoperative liver function in patients with preoperatively elevated liver enzyme levels (aspartate transaminase [AST] or alanine transaminase [ALT] > 40 U/L) who had undergone non-hepatic surgery under general anesthesia. The alterations in enzyme levels within 24 hrs before and after surgery were compared. This study enrolled a total of 730 patients (TIVA: n=138; INHA: n=592), the baseline characteristics were comparable, except for higher comorbidity rates in the TIVA group. The results suggest that TIVA may be safe and effective for individuals with preoperatively elevated liver transaminase levels.