Shuster A, et al. - Researchers compared the histopathological parameters of chronic/suppurative osteomyelitis, medication-related osteonecrosis of the jaw (MRONJ), and osteoradionecrosis (ORN), and examined the presumption that distinct histological features can be related to a specific disease, allowing for diagnosis based on microscopic evaluation alone. Distinctive microscopic characteristics could not be identified in any of the 3 entities that could be used to differentiate between them. Hence, reaching a specific final diagnosis is impossible based on microscopic findings alone. Microscopic analysis served as an aid to diagnosis that must be complemented by the patient’s history and imaging.