Huh J, et al. - A total of 60 individuals older than 60 years who underwent lumbar fusion surgeries were randomized to groups M (milrinone), S (sodium nitroprusside), and N (nitroglycerine) in order to contrast the impacts of milrinone with those of other vasodilating hypotensive agents on induced hypotension in old people who were undergoing spine surgery. Intraoperative blood loss per fused spine level was 288.5 ± 94.4 mL, 399.8 ± 60.3 mL, and 367.0 ± 122.5 mL, in group M, S, and N, respectively. Among the three groups, the grade of the surgical field was comparable. Hourly urine output was 1.4 ± 0.5 mL, 0.7 ± 0.3 mL, and 0.9 ± 0.4 mL in group M, group S, and group N, respectively. Therefore, in old people who underwent spine surgery, for induced hypotension, the use of milrinone resulted in less intraoperative blood loss and greater urine output in comparison with the use of sodium nitroprusside or nitroglycerine.