Higgins C, et al. - Treatment-seeking, opioid-dependent patients with vs without chronic pain were compared in terms of psychiatric morbidity in this retrospective comparative cohort study. Among the 467 patients included from an NHS Substance Misuse Service in the East of Scotland, chronic pain was reported in 52.7% and no pain was reported in 47.3%. A higher proportion of patients with chronic pain reported at ≥ 1 psychiatric morbidity (62.4% vs 46.3%) and were prescribed anxiolytics (49.0 vs 39.1%) and antimanic drugs (9.9 vs 4.9%). Findings thus suggested the possibility for a higher prevalence of psychiatric comorbidity among patients who report chronic pain vs those who do not.