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Comparison of prognostic impact of lymphovascular invasion in stage IA non- small cell lung cancer after lobectomy vs sublobar resection: A propensity score-matched analysis

Lung Cancer Jul 22, 2020

Yun JK, Lee GD, Choi S, et al. - For non-small cell lung cancer, lymphovascular invasion (LVI) is a clear poor prognostic factor following lobectomy, so researchers investigated if LVI had any prognostic impact in stage IA patients who underwent lobectomy or sublobar resection. They included 2,134 patients with stage IA non-small cell lung cancer (NSCLC). LVI was diagnosed in 184 patients (8.6%) of them; 144 (8.9%) were in the lobectomy group (n = 1,614) and 40 (7.7%) were in the sublobar resection group (n = 520). In stage IA NSCLC patients, findings revealed a significant correlation of the presence of LVI with worse overall survival and recurrence-free survival. The sublobar resection group showed a more pronounced prognostic impact of LVI vs the lobectomy group.

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