Matsumura-Nakano Y, Shiomi H, Morimoto T, et al. - Since there exists a paucity of data comparing long-term clinical results between percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) in patients suffering from three-vessel coronary artery disease (3VD) in the new-generation drug-eluting stents era, therefore, researchers explored this topic by analyzing consecutive patients enrolled in CREDO-Kyoto PCI/CABG registry Cohort-3, who had received first coronary revascularization with PCI or isolated CABG between January 2011 and December 2013. Overall 2,525 patients with 3VD (PCI: N=1747 [69%], and CABG: N=778 [31%]) were identified. All-cause death was assessed as the primary outcome measure. A significantly higher risk for all-cause death was reported in relation to PCI vs CABG in this study population reflecting real-world clinical practice in Japan, while experts found no excess risk for cardiovascular death between PCI and CABG.