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Comparison of mortality and readmission in non-ischemic vs ischemic cardiomyopathy after implantable cardioverter-defibrillator implantation

The American Journal of Cardiology Jul 29, 2020

Higgins AY, Bjerre J, Parzynski CS, et al. - Since there is a lack of data regarding the contemporary risk of mortality and readmission after implantable cardioverter-defibrillator (ICD) implantation among patients with non-ischemic cardiomyopathies (NIC) vs ischemic cardiomyopathies (IC) in a large nationally representative cohort, so, researchers undertook this retrospective cohort analysis utilizing the National Cardiovascular Data Registry ICD Registry joined with Medicare claims from April 1, 2010 to December 31, 2013. This study involved a cohort comprising NIC and IC patients with a left ventricular ejection fraction ≤ 35% who received a de novo, primary prevention ICD. Kaplan-Meier curves and Cox proportional hazard regressions models were employed to compare death and readmission. Findings showed significantly higher risks of death and hospital readmission following primary prevention ICD implantation in patients with IC vs NIC which was identified to be consistent across all patient subgroups examined and over the span of the study.

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