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Comparison of methods used to correct self-reported protein intake for systematic variation in reported energy intake using quantitative biomarkers of dietary intake

The Journal of Nutrition Feb 17, 2020

Korth AL, Bhutani S, Neuhouser ML, et al. - Researchers performed a comparison between 5 energy-correction methods for self-reported dietary protein against urinary nitrogen–derived protein consumption. A total of 544 individuals (50- to 80-y-old women) participating in the WHI Nutritional Biomarkers Study (NBS) were examined. The correction methods assessed were as follows: DLW (doubly labeled water)-TEE (total energy expenditure); the Institute of Medicine's (IOM's) estimated energy requirement (EER) TEE prediction equation based on gender, height, weight, and age; published NBS total energy TEE prediction (WHI-NBS-TEE) using age, BMI, race, and income; reported protein vs reported energy linear regression–based residual method; and a Goldberg cutoff to exclude individuals stating energy intakes < 1.35 times their basal metabolic rate. According to the findings, modestly better performance of measures of energy requirement from DLW-TEE or IOM-EER vs other methods was evident for the proportional correction of reported protein intake. These energy adjustments, however, afforded corrected protein exceeding the biomarker protein, suggesting that all self-reported protein reporting bias was not eliminated by energy adjustment alone.
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