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Comparison between the efficacy of microneedling combined with 5-fluorouracil vs microneedling with tacrolimus in the treatment of vitiligo

Journal of Cosmetic Dermatology Jun 19, 2018

Mina M, et al. - Experts evaluated the effectiveness of microneedling with 5-flurouracil vs its efficacy with tacrolimus in the treatment of vitiligo. They included 25 patients with vitiligo and subjected them to microneedling of 2 patches of vitiligo with dermapen, then application of 5-fluorouracil to 1 patch and tacrolimus on the other patch. Results demonstrated safety and effectiveness of microneedling combined with 5-fluorouracil or tacrolimus as the treatment of vitiligo. Nonetheless, a higher percentage of repigmentation was achieved with 5-fluorouracil vs tacrolimus, particularly in the acral parts.
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