Chi H, et al. - A comparative contemplation was performed of the ongoing pregnancy rate in patients receiving IVF/ICSI-ET therapy with Crinone vaginal gel or intramuscular progesterone (IMP) for luteal phase support. The data deduced that the efficacy of progesterone vaginal gel was non-inferior to the IMP for luteal phase support in IVF/ICSI-ET. The variation of luteal phase bleeding did not impact the biochemical pregnancy outcome. Hence, progesterone vaginal gel could serve as a choice other than intramuscular progesterone for luteal support in ART.