Yenihayat F, et al. – This analysis encompassed the description of metabolic processes playing roles in the formation of keratoconus (KC). The data disclosed that the involvement of NADHX repair pathway in KC ought to undergo assessment since preliminary clues obtained in this study pointed to that direction. Illustrating the presence of ATP–dependent NAD(P)H–hydrate dehydratase that eliminated NADHX would lead to a strengthening of the results and would be a major step towards comprehending KC.