Comparative effectiveness of glycemic control in patients with type 2 diabetes treated with GLP-1 receptor agonists: A network meta-analysis of placebo-controlled and active-comparator trials
Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy | Aug 24, 2017
Orme ME, et al. – A Bayesian network meta–analysis (NMA) of placebo– and active–controlled randomized trials was conducted to evaluate the comparative effectiveness of liraglutide, albiglutide, dulaglutide, and exenatide twice daily and once weekly, with a focus on glycemic control. It was concluded that GLP–1 receptor agonists (GLP–1 RAs) are a viable addition to oral antidiabetes therapy, and dulaglutide, exenatide once weekly, and liraglutide are the most effective.
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