Chou IJ, et al. - At multiple sclerosis (MS) diagnosis, researchers determined the burden of comorbidities, the risk of developing new comorbidities following diagnosis, and the impact of comorbidities on mortality in MS patients. This research used data from the UK Clinical Practice Research Datalink for 2,526 patients with incident MS and 9,980 age, sex, and physician-matched non-MS controls. Investigators found that MS correlated with higher cardiovascular and neurological/mental disease risks. The adjusted hazard ratio for the connection between MS and an increased risk of developing comorbidities was 1.13 following diagnosis. There was a greater risk of developing comorbidity in MS in terms of neoplasms, musculoskeletal/connective tissue illnesses, or neurological/mental illnesses. Findings suggested that patients with MS have an enhanced risk of numerous pre- and post-diagnosis comorbidities and pre-existing comorbidities have an effect on survival.