Dyer AH, McKenna L, Gamage G, et al. - Researchers conducted a cross‐sectional study of middle‐aged adults with uncomplicated type 2 diabetes vs a cohort of healthy control participants to assess the impact of type 2 diabetes on cognitive performance in mid-life. They evaluated general cognition applying the Montreal Cognitive Assessment test and neuropsychological assessment was performed applying a detailed neuropsychological assessment battery. The study included 152 individuals (102 with type 2 diabetes and 50 controls, mean age 52 ± 8 years, 51% women). Those with type 2 diabetes in midlife were more than twice as likely to make an error on the Montreal Cognitive Assessment test. After adjustment for age, sex, BMI, educational attainment and hypercholesterolaemia, type 2 diabetes was correlated with significantly lower memory composite score and paired associates learning score on the neuropsychological assessment battery. The data revealed that type 2 diabetes was associated with small but statistically significant cognitive decrements, even in midlife. It was reported that these statistically significant decrements, while not clinically significant in terms of objective cognitive impairment, could have important implications targeting those at higher risk of later cognitive decline for potential preventative interventions.