Zanelli J, Mollon J, Sandin S, et al. - The researchers examined participants from a population-based case-control study of patients with first-episode psychosis to assess cognition in schizophrenia patients after the first episode. In addition, they ascertained if this decline is generalized or confined to individual neuropsychological functions and if decline is specific to schizophrenia. Prospective follow-up data for 10 years after the first admission of the participants were analyzed. Patients with a diagnosis of schizophrenia (N = 65) or other psychoses (N = 41) as well as healthy comparison people (N = 103) were administered a neuropsychological battery at index presentation and at follow-up. Cognitive decline was reported by the patients with schizophrenia and other psychoses following illness onset, but there was a variation in the magnitude of decline across cognitive functions ranging between 0.28 and 0.66 standard deviations. At the first episode, the presence of processing speed and executive function impairments was reported which remained stable thereafter. They suggest that impairments across different cognitive functions could be due to distinct mechanisms consequent to the illness and/or psychosocial factors.