Yoo HS, et al. - Researchers conducted this cross-sectional study to examine cognitive anosognosia in de novo patients with Parkinson disease (PD) and analyze its connection to cognitive function and neuropsychiatric symptoms. Study participants included 340 drug-naïve patients with PD. Patients were classified as patients with cognitive anosognosia (PD-CA, n = 74), with normal cognitive recognition (PD-NR, n = 184), or with cognitive underestimation (PD-CU, n = 82), depending on the presence of mild cognitive impairment (MCI) and subjective cognitive complaint. In 21.8% of individuals with de novo PD, cognitive anosognosia was found. Findings suggested an association of cognitive anosognosia in PD with greater frontal dysfunction and lower depression. Due to overestimation of their abilities in everyday life, early identification of cognitive anosognosia in PD is important in management and prognosis since cognitive anosognosia has a harmful impact on PD patients and their caregivers. The association between cognitive anosognosia and Beck Depression Inventory score was mediated by the Cognitive Complaints Interview score.