Owusu JE, et al. – Researchers assessed the impact of 25-hydroxyvitamin D (25(OH)D) levels recommended by Endocrine Society guidelines (> 30 ng/mL) on cognition in healthy older African American women over 3 years in this randomized, double-blind, placebo-controlled clinical trial. Study participants included healthy postmenopausal African American women aged ≥ 65 years (N=260; mean age 68.2 ± 4.9; 46% college education or higher). Patients were randomized to receive either vitamin D (adjusted to achieve a serum level > 30 ng/mL) with calcium (diet and supplement total of 1,200 mg) or placebo with calcium (1,200 mg). Findings revealed that cognition was not different over time between older African American women with serum concentrations of 25(OH)D of ≥ 30 ng/mL vs those taking placebo. These findings, therefore, did not support vitamin D intake greater than the recommended daily allowance for the prevention of cognitive decline in this population.